Bdparp 150 mg Tablet – Precision Therapy for Cancer Treatment
Bdparp 150 mg Tablet also known as Lynparza contains olaparib, a PARP (poly ADP-ribose polymerase) inhibitor used primarily to treat certain types of cancers by interfering with DNA repair in cancer cells, ultimately causing cell death and slowing tumor growth.
Uses:
- Ovarian Cancer: Used for maintenance treatment in patients with advanced ovarian cancer who have responded to platinum-based chemotherapy.
- Breast Cancer: Approved for use in patients with BRCA-mutated, HER2-negative breast cancer.
- Prostate Cancer: Used for patients with metastatic castration-resistant prostate cancer (mCRPC) who have specific genetic mutations.
- Pancreatic Cancer: Treats BRCA-mutated, metastatic pancreatic cancer following a response to platinum-based chemotherapy.
How Bdparp 150 mg Tablet Works:
Olaparib inhibits the activity of the PARP enzyme involved in DNA repair. By blocking PARP, cancer cells with defects in BRCA1/BRCA2 or other DNA repair genes are unable to repair themselves effectively, leading to cell death. This targeted approach helps control cancer growth and progression.
Common Side Effects:
- Nausea
- Fatigue
- Anemia
- Vomiting
- Decreased appetite
Serious Side Effects (Seek Immediate Medical Attention):
- Severe fatigue or shortness of breath (signs of anemia)
- Unexplained bruising or bleeding
- Symptoms of infection, such as fever or chills
- Lung problems, including new or worsening cough, difficulty breathing, or chest pain
Key Features:
- Contains olaparib, a PARP inhibitor for targeted cancer therapy
- Available in oral tablet form for convenient administration
- Approved for use in various BRCA-mutated cancers
- Helps improve survival outcomes in eligible patients with specific genetic mutations
Precautions:
- Pregnancy Warning: Bdparp 150 mg Tablet is not recommended during pregnancy as it can harm the unborn baby. Effective contraception must be used during treatment.
- Hematological Monitoring: Patients should undergo regular blood tests to monitor for anemia or other blood disorders.
- Potential Drug Interactions: Inform your healthcare provider about all medications being taken, as olaparib may interact with other drugs.
Frequently Asked Questions (FAQ):
What is Bdparp 150 mg Tablet used for?
It is used to treat certain types of cancers, such as ovarian, breast, prostate, and pancreatic cancers, particularly in patients with specific genetic mutations.
How does Bdparp 150 mg Tablet work?
It works by inhibiting the PARP enzyme, leading to impaired DNA repair in cancer cells and causing their death.
Is Bdparp safe during pregnancy?
No, it is not recommended for use during pregnancy as it can harm the fetus. Women of reproductive age must use effective contraception during treatment.
References:
- FDA Olaparib Information – https://www.medicines.org.uk/emc/product/9488/smpc
- European Medicines Agency – https://www.ema.europa.eu/en/documents/product-information/lynparza-epar-product-information_en.pdf
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