Carmendan 12.5 mg Injection contains Levosimendan, a calcium sensitizer and potassium channel opener used to improve heart function in critical care settings.

Uses:

✔ Acute Decompensated Heart Failure – Rapidly improves cardiac output in hospitalized patients
✔ Cardiogenic Shock – Stabilizes hemodynamic status in ICU
✔ Low Cardiac Output Post-Surgery – Used post cardiac surgery to prevent heart failure
✔ Bridge Therapy for Heart Transplant – Enhances cardiac support pre-transplant
✔ End-Stage Heart Failure – Palliative inotropic support

How Carmendan Works:

Levosimendan increases the sensitivity of the heart muscle to calcium, enhancing contractility without increasing oxygen demand. It also opens potassium channels, causing vasodilation, which reduces the workload on the heart and improves circulation.

Dosage & Administration:

• IV infusion only, typically administered in a hospital ICU setting

• Loading dose: 6–12 mcg/kg over 10 minutes, followed by a continuous infusion

• Infusion rate: 0.05–0.2 mcg/kg/min over 24 hours

• Not for bolus use outside hospital setting

Common Side Effects:

• Headache

• Hypotension (low blood pressure)

• Nausea

• Dizziness

• Increased heart rate

Serious Side Effects (Seek Medical Help):

⚠ Ventricular arrhythmias
⚠ Hypotension requiring intervention
⚠ Electrolyte imbalances
⚠ Worsening renal function
⚠ Myocardial ischemia (rare)

Precautions:

⚡ Blood Pressure Monitoring: Required throughout infusion
⚡ Avoid in Severe Hypotension: Not suitable if systolic BP < 85 mmHg
⚡ Kidney Function: Adjust dose or avoid in severe renal impairment
⚡ Not for Long-Term Use: Designed for short-term acute support
⚡ Pregnancy & Breastfeeding: Use only if benefits outweigh risks

FAQs – Frequently Asked Questions

What is Carmendan 12.5 mg used for?
Carmendan is used for short-term treatment of acute heart failure and cardiogenic shock, especially when conventional treatments fail.

How is Carmendan administered?
It is given intravenously in a hospital ICU, with careful monitoring of heart rhythm, blood pressure, and kidney function.

Is Carmendan better than dobutamine?
Levosimendan offers inotropic support without increasing myocardial oxygen consumption, making it preferable in some cases over traditional inotropes like dobutamine.

Can Carmendan be used long-term?
No, it is intended for short-term use only during acute heart failure episodes or bridging to transplant.

Where can I buy Carmendan 12.5 mg Injection online?
Buy Carmendan online from Milan Medicals for authentic Levosimendan injection at the best price, with worldwide shipping and prescription support.

References:

🔗 https://go.drugbank.com/drugs/DB00922
🔗 https://janesthanalgcritcare.biomedcentral.com/articles/10.1186/s44158-021-00030-7