Denu 60mg Injection

Denu 60mg Injection serves as a reliable and more accessible alternative to brand-name Denosumab therapies. It targets the RANKL protein, which signals the body to break down bone tissue. By inhibiting this protein, Denu allows the body’s natural bone-building process to thrive, leading to thicker, more resilient bones. This is especially vital for individuals with age-related bone thinning or those whose medications (like steroids or hormonal cancer therapies) are causing secondary bone loss.

Key Benefits of Denu 60mg Injection

• High Efficacy: Significantly increases bone mineral density in the spine and hip.

• Reduced Fracture Risk: Lowers the likelihood of vertebral, non-vertebral, and hip fractures.

• Convenient Bi-Annual Dose: Requires only two injections per year, ensuring better patient compliance than daily oral medications.

• Oncology & Hormonal Support: Protects bone health in men with prostate cancer and women with breast cancer receiving hormone-lowering treatments.

Clinical Administration & Proper Care

1. Professional Use Only: Denu must be administered by a healthcare professional as a subcutaneous injection (usually in the thigh, abdomen, or upper arm).

2. Calcium & Vitamin D: To ensure maximum effectiveness and safety, it is often recommended to take Calcium and Vitamin D supplements during treatment.

3. Strict Temperature Control: Must be stored in a refrigerator (2°C to 8°C). Do not freeze or shake.

4. Dental Health: Patients should maintain good oral hygiene and inform their dentist they are using Denosumab, as it can rarely affect the jawbone.

Frequently Asked Questions (FAQs)

1. Is Denu 60mg the same as Prolia? Yes. Denu contains Denosumab, the same active ingredient found in Prolia. It is a biosimilar manufactured by Alkem Laboratories, offering the same therapeutic benefits for bone health.

2. How often do I need to take Denu? For most patients with osteoporosis, Denu is administered as a single 60mg injection once every 6 months.

3. Does Denu require cold-chain shipping to the UAE or USA? Yes. Since Denosumab is a protein-based biologic, it must stay refrigerated. Milan Medicals uses specialized cold-chain packaging to ensure Denu remains between 2°C and 8°C during delivery to the USA, UAE, KSA, and UK.

4. What are the common side effects of Denu 60mg? The most common side effects include back pain, pain in the arms or legs, and musculoskeletal pain. Less common but serious side effects can include low calcium levels or skin infections (cellulitis).

5. Can I use Denu if I have kidney problems? Denu is generally safe for patients with kidney disease and does not usually require dose adjustments, but you should always consult your doctor as they will need to monitor your calcium levels more closely.

References:

1. Amgen Inc. “Prolia (denosumab) injection, for subcutaneous use.” U.S. Food and Drug Administration. [Revised on 2021 Dec; Accessed on 5 Nov 2024]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK535388/
2. European Medicines Agency (EMA). “Denosumab (Denu) Product Information.” [Accessed on 5 Nov 2024]. Available from: https://medlineplus.gov/druginfo/meds/a610023.html