Jakavi 20 mg Tablet contains Ruxolitinib, a Janus kinase (JAK1 and JAK2) inhibitor used in treating certain types of blood cancers and immune conditions.

Uses:

✔ Myelofibrosis – Treats enlarged spleen and improves symptoms in adults with intermediate/high-risk disease
✔ Polycythemia Vera – Helps control red blood cell production and reduces thrombotic risk
✔ Graft-versus-Host Disease (GVHD) – Approved for steroid-refractory acute and chronic GVHD
✔ Off-label – Investigated in alopecia areata and COVID-related inflammation (consult doctor)

How Jakavi Works:

Ruxolitinib blocks overactive JAK1 and JAK2 enzymes involved in immune and blood cell production. This helps reduce inflammation, regulate abnormal blood cell counts, and shrink spleen size in myeloproliferative disorders.

Dosage & Administration:

• Dosage is patient-specific, based on platelet count and condition

• Typically taken orally twice a day with or without food

• Dosage adjustment may be required for liver/kidney impairment or drug interactions

• Continuous CBC monitoring is essential

Common Side Effects:

• Headache

• Dizziness

• Bruising

• Anemia

• Infections (UTI, herpes, pneumonia)

Serious Side Effects (Seek Medical Help):

⚠ Severe infections (tuberculosis, fungal, viral)
⚠ Blood disorders (low WBC, RBC, platelet counts)
⚠ Liver function abnormalities
⚠ Elevated cholesterol
⚠ Non-melanoma skin cancers (long-term use)

Precautions:

⚡ Infection Risk: Screen for TB and hepatitis before starting
⚡ Blood Monitoring: Regular CBC tests required
⚡ Pregnancy & Breastfeeding: Not recommended
⚡ Immunosuppression: Avoid live vaccines during treatment
⚡ Liver & Kidney Function: May need dose modification

FAQs – Frequently Asked Questions

What is Jakavi 20 mg used for?
Jakavi is used for treating myelofibrosis, polycythemia vera, and steroid-refractory graft-versus-host disease (GVHD).

How long does Jakavi take to work?
Most patients begin seeing spleen size reduction and symptom relief within 2–4 weeks of treatment.

Can Jakavi cause low blood counts?
Yes, it can lower platelets, red and white blood cells—regular blood monitoring is essential.

Is Jakavi a chemotherapy drug?
No, Jakavi is a targeted oral JAK inhibitor, not a traditional chemotherapy agent.

Where can I buy Jakavi 20 mg Tablet online?
Buy Jakavi 20 mg online from Milan Medicals for authentic, affordable medication with worldwide delivery.

References:

🔗 https://www.medicines.org.uk/emc/product/7784/smpc
🔗 https://medbroadcast.com/drug/getdrug/jakavi