Lasinone 10 mg Capsule 60’s

Lasinone 10 mg Capsule contains nitisinone, a medication primarily used for the treatment of hereditary tyrosinemia type 1 (HT-1), a rare genetic disorder affecting the breakdown of the amino acid tyrosine. By inhibiting an enzyme involved in tyrosine metabolism, nitisinone helps reduce the toxic byproducts that cause liver and kidney damage in HT-1 patients.

Uses:

1. Treatment of Hereditary Tyrosinemia Type 1 (HT-1): Reduces levels of toxic tyrosine breakdown byproducts to prevent liver and kidney damage.
2. Additional Indications: Nitisinone may be studied for other conditions, such as alkaptonuria, under medical supervision.

How Lasinone 10 mg Capsule Works:

Nitisinone works by inhibiting the enzyme 4-hydroxyphenylpyruvate dioxygenase (HPPD), which is involved in tyrosine breakdown. By blocking this enzyme, nitisinone prevents the formation of harmful substances in the body, effectively managing the symptoms and progression of HT-1.

Common Side Effects:

• Elevated tyrosine levels (may lead to eye or skin issues)
• Headache
• Nausea
• Abdominal pain

Serious Side Effects (Seek Immediate Medical Attention):

• Visual disturbances: Indicating elevated tyrosine levels.
• Liver issues: Monitor for signs like yellowing skin/eyes or abdominal pain.

Key Features:

• Contains nitisinone, an enzyme inhibitor for managing tyrosine metabolism disorders.
• Prevents liver and kidney damage associated with hereditary tyrosinemia type 1.
• Effective when combined with a low-tyrosine, low-phenylalanine diet.
• Administered orally under medical guidance.

Precautions:

• Diet Management: Requires adherence to a low-tyrosine, low-phenylalanine diet.
• Monitoring: Regular blood tests to monitor tyrosine levels.
• Pregnancy Safety: Should only be used if prescribed during pregnancy; consult your healthcare provider.

Frequently Asked Questions (FAQ):

1. What is Lasinone 10 mg Capsule used for?
   It is used to treat hereditary tyrosinemia type 1 (HT-1) by reducing toxic tyrosine byproducts that can damage the liver and kidneys.
2. How should Lasinone be taken?
   It should be taken orally, typically under the guidance of a healthcare provider, and in conjunction with a special diet.
3. Are there any special dietary recommendations?
   Yes, patients need to follow a low-tyrosine, low-phenylalanine diet while taking Lasinone.
4. Can Lasinone be used during pregnancy?
   Use during pregnancy should be discussed with a healthcare provider to weigh benefits and risks.

References:

1. Nitisinone Medication Overview
   Available from: https://www.mayoclinic.org/drugs-supplements/nitisinone-oral-route/description/drg-20065062
   Accessed on: November 11, 2024.
2. FDA – Tyrosinemia Treatments
   Available from: https://www.ncbi.nlm.nih.gov/books/NBK589678/
   Accessed on: November 11, 2024.