Stelara 90mg Injection

Stelara 90mg Injection – Targeted Therapy for Autoimmune Diseases

Stelara 90mg Injection contains ustekinumab, a monoclonal antibody used to treat autoimmune conditions such as plaque psoriasis, psoriatic arthritis, Crohn’s disease, and ulcerative colitis. Ustekinumab works by targeting specific proteins in the immune system, interleukin-12 (IL-12) and interleukin-23 (IL-23), which play a role in inflammation and immune response.

Uses:

• Moderate to Severe Plaque Psoriasis: Used for adult patients who are candidates for systemic therapy or phototherapy.
• Active Psoriatic Arthritis: Indicated alone or in combination with methotrexate for adult patients.
• Moderate to Severe Crohn’s Disease: For patients who have not responded well to other therapies.
• Ulcerative Colitis: Helps reduce inflammation and symptoms in moderate to severe cases.

How Stelara 90mg Injection Works:

Ustekinumab selectively inhibits the activity of IL-12 and IL-23, proteins that contribute to inflammatory responses in autoimmune diseases. By blocking these proteins, Stelara helps reduce symptoms like redness, pain, and swelling.

Common Side Effects:

• Nasopharyngitis (common cold)
• Headache
• Fatigue
• Upper respiratory infections
• Injection site reactions

Serious Side Effects (Seek Immediate Medical Attention):

• Infections: Increased risk of serious infections, including tuberculosis.
• Cancer Risk: Possible increased risk of certain cancers.
• Allergic Reactions: Signs include rash, itching, or difficulty breathing.

Key Features:

• Contains ustekinumab, a biologic therapy that targets IL-12 and IL-23.
• Reduces immune system overactivity to manage autoimmune disease symptoms.
• Effective for multiple autoimmune conditions such as psoriasis and Crohn’s disease.
• Administered as a subcutaneous injection under medical supervision.

Precautions:

• Pregnancy Warning: Use only if the potential benefit justifies the risk to the fetus. Discuss with your healthcare provider.
• Screening for Tuberculosis: Patients should be screened for latent tuberculosis before starting Stelara.
• Immunosuppressive Effects: Patients may experience a higher risk of infections.

Frequently Asked Questions (FAQ):

1. What is Stelara 90mg Injection used for?
   Stelara treats plaque psoriasis, psoriatic arthritis, Crohn’s disease, and ulcerative colitis by reducing inflammation through IL-12 and IL-23 inhibition.
2. How is Stelara administered?
   It is given as a subcutaneous injection, typically administered under the guidance of a healthcare professional.
3. Is Stelara safe during pregnancy?
   Stelara should only be used during pregnancy if absolutely necessary. Consult your healthcare provider.
4. Does Stelara suppress the immune system?
   Yes, it can suppress the immune response, increasing the risk of infections.
5. What if I miss a dose?
   Contact your healthcare provider to determine the appropriate next steps.

References:

1. Janssen Biotech, Inc. – Stelara (Ustekinumab) Product Information
   Available from: https://www.stelara.com
   Accessed on: November 10, 2024.
2. European Medicines Agency – Ustekinumab Information
   Available from: https://www.ema.europa.eu/en/medicines/human/EPAR/stelara
   Accessed on: November 10, 2024.