Tenectelex Tenecteplase 40 mg Injection

Tenectelex Tenecteplase 40 mg Injection  is engineered to be more resistant to inactivation by natural inhibitors in the body than earlier generations of clot-busters. This ensures that the 40 mg dose remains active long enough to clear the blockage with a single 5–10 second injection.

Key Clinical Benefits

• Rapid Reperfusion: Quickly restores oxygen-rich blood flow to the heart, significantly improving survival rates.

• High Fibrin Specificity: Targets the clot itself with minimal impact on the body's overall clotting system, reducing the risk of systemic bleeding.

• Single-Bolus Convenience: Unlike older drugs requiring long infusions, Tenectelex is administered in one quick push, ideal for ambulance or ER use.

• Proven Efficacy: Extensively used in India and globally to treat STEMI, showing comparable outcomes to primary PCI (angioplasty) when performed early.

Administration & Cold-Chain Protocols

1. Emergency Use Only: Must be administered by a qualified healthcare professional in a hospital or emergency setting.

2. Weight-Based Dosing: The 40 mg strength is typically used for patients weighing ≥70 to <80 kg. Always verify the patient's weight before administration.

3. Reconstitution: Use the provided pre-filled syringe of sterile water to dissolve the powder. Swirl gently; do not shake.

4. Strict Storage: Must be stored in a refrigerator at 2°C to 8°C (36°F to 46°F). Protect from light.

5. Time Sensitivity: For maximum benefit, Tenectelex should be administered within 6 hours (ideally within 3 hours) of the onset of heart attack symptoms.