Tykerb 250 mg Tablet 30’s

Tykerb 250 mg Tablet – Lapatinib for Breast Cancer Treatment

Tykerb 250 mg Tablet contains lapatinib, a tyrosine kinase inhibitor used in the treatment of HER2-positive breast cancer. Lapatinib works by inhibiting the growth of cancer cells by targeting and blocking proteins that promote cancer cell growth, specifically HER2/neu (ErbB2) and EGFR (epidermal growth factor receptor).

Uses:

1. HER2-Positive Breast Cancer: Used in combination with other medications, such as capecitabine, for the treatment of advanced or metastatic breast cancer in patients whose disease has progressed on other HER2-targeting treatments (e.g., trastuzumab).
2. Combination Therapy: Often prescribed alongside other chemotherapy drugs for improved effectiveness against cancer cells.

How Tykerb 250 mg Tablet Works:

Lapatinib targets and binds to the HER2/neu and EGFR receptors present on the surface of certain cancer cells. By blocking the signaling pathways, it prevents cancer cells from growing and dividing, slowing the progression of the disease.

Common Side Effects:

• Diarrhea
• Nausea
• Fatigue
• Rash
• Loss of appetite

Serious Side Effects (Seek Immediate Medical Attention):

• Heart Problems: Symptoms such as chest pain, shortness of breath, or irregular heartbeat.
• Liver Toxicity: Yellowing of the skin/eyes, dark urine, or abdominal pain.
• Severe Diarrhea: Can lead to dehydration; medical monitoring may be necessary.

Key Features:

• Contains lapatinib, a tyrosine kinase inhibitor targeting HER2/neu.
• Effective for advanced or metastatic HER2-positive breast cancer.
• Often used in combination therapy for improved cancer control.
• Taken orally for convenient administration.

Precautions:

• Pregnancy and Lactation: Not to be used during pregnancy or while breastfeeding due to potential harm to the baby.
• Heart Monitoring: Patients may require regular monitoring for heart function.
• Drug Interactions: Inform your doctor of all medications to avoid interactions.

Frequently Asked Questions (FAQ):

1. What is Tykerb used for?
   Tykerb is used to treat HER2-positive advanced or metastatic breast cancer, often combined with other chemotherapy agents.
2. How is Tykerb taken?
   It is typically taken orally, with or without food, as prescribed by a healthcare provider. Doses must be taken at consistent times daily.
3. Can Tykerb cause heart problems?
   Yes, Tykerb may affect heart function, so regular monitoring and reporting of symptoms like chest pain or shortness of breath are important.
4. Is Tykerb suitable for all breast cancer patients?
   Tykerb is specifically for HER2-positive breast cancer patients. Suitability will be determined by your healthcare provider.

References:

1. GlaxoSmithKline – Lapatinib Product Information
   Available from: https://go.drugbank.com/drugs/DB01259
   Accessed on: November 11, 2024.
2. National Cancer Institute – Tyrosine Kinase Inhibitors
   Available from: https://reference.medscape.com/drug/tykerb-lapatinib-342235
   Accessed on: November 11, 2024.