Venclexta 100 mg Tablet

Venclexta 100 mg Tablet contains Venetoclax, an oral selective BCL-2 inhibitor used to treat certain blood cancers.

Uses:

✔ Chronic Lymphocytic Leukemia (CLL) – With or without 17p deletion, in adults
✔ Acute Myeloid Leukemia (AML) – In newly diagnosed elderly patients or those unfit for intensive chemotherapy
✔ Small Lymphocytic Lymphoma (SLL) – A closely related blood cancer

How Venclexta Works:

Venetoclax selectively binds and inhibits the BCL-2 protein, which helps cancer cells survive. By blocking BCL-2, Venclexta triggers cancer cell death (apoptosis) and reduces tumor burden.

Dosage & Administration:

• Starting Dose: Titrated gradually to reduce tumor lysis syndrome risk

• Typical Ramp-up: 20 mg → 50 mg → 100 mg → 200 mg → 400 mg over 5 weeks

• Maintenance Dose: 400 mg daily (CLL); 400–600 mg daily with chemotherapy (AML)

• Administration: Take orally once daily with food and water

• Hydration & Monitoring: Required to prevent tumor lysis syndrome

Common Side Effects:

• Neutropenia (low white blood cells)

• Diarrhea

• Nausea

• Fatigue

• Upper respiratory infections

Serious Side Effects (Seek Medical Help):

⚠ Tumor lysis syndrome (TLS)
⚠ Severe neutropenia leading to infections
⚠ Anemia and thrombocytopenia
⚠ Pneumonia
⚠ Severe gastrointestinal issues

Precautions:

⚡ Tumor Lysis Syndrome: Careful monitoring, premedication, and dose escalation
⚡ Infection Risk: Monitor for fever, chills, or new infections
⚡ Drug Interactions: CYP3A inhibitors (e.g., ketoconazole) require dose adjustment
⚡ Pregnancy & Breastfeeding: Not recommended; contraception required
⚡ Renal Impairment: Extra caution needed during dose initiation

FAQs – Frequently Asked Questions

What is Venclexta used for?
Venclexta treats CLL, SLL, and AML by promoting programmed cancer cell death.

Can Venclexta be used alone or with other therapies?
Yes, it can be used as a single agent or in combination with other chemotherapy or targeted agents.

Why does Venclexta have a gradual ramp-up schedule?
To reduce the risk of tumor lysis syndrome, a life-threatening complication from rapid cancer cell death.

Should Venclexta be taken with food?
Yes, always take Venclexta with food to improve absorption and reduce side effects.

Where can I buy Venclexta 100 mg online?
Buy genuine Venetoclax tablets from Milan Medicals with worldwide shipping at competitive prices.

References:

🔗 https://www.webmd.com/drugs/2/drug-171573/venclexta-oral/details
🔗 https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/208573s013lbl.pdf