Evenity Injection

Evenity Injection works by inhibiting Sclerostin, a protein that naturally limits bone formation. By blocking this protein, Evenity signals the body to rapidly create new, high-quality bone while simultaneously reducing the rate at which old bone is broken down. This “dual effect” leads to a dramatic increase in bone mineral density (BMD) within just one year, significantly lowering the risk of spine and hip fractures.

Why Evenity is a Breakthrough in Osteoporosis

• Rapid Bone Growth: Significantly increases bone density in the lumbar spine and hip in just 12 months.

• Superior Fracture Prevention: Clinical trials show a 73% reduction in the risk of new vertebral fractures compared to placebo after one year.

• Fixed-Term Therapy: A convenient 12-month treatment course, after which patients typically transition to a maintenance therapy like Prolia (Denosumab).

• Targeted for High-Risk: Specifically designed for women who have already experienced a fracture or have failed other treatments like bisphosphonates.

Clinical Administration & Storage Guidelines

1. Full Dose Requirement: One monthly dose is 210 mg, which requires two separate 105 mg injections given one after the other.

2. Injection Sites: Subcutaneous injection in the abdomen, thigh, or upper arm. Sites should be rotated monthly.

3. Mandatory Refrigeration: Must be stored at 2°C to 8°C (36°F to 46°F).

4. Handling: Take the syringes out of the fridge 30 minutes before injection to reach room temperature (do not warm in other ways). Do not shake or freeze.

Frequently Asked Questions (FAQs)

1. How is Evenity different from Prolia? Evenity is a bone builder (anabolic) that increases bone formation and is taken for only 12 months. Prolia is an anti-resorptive that slows down bone loss and is typically taken every 6 months for a longer duration.

2. Can Men use Evenity? Currently, Evenity is only FDA-approved for use in postmenopausal women. While studies have been conducted in men, it is not currently the standard approved indication.

3. What is the “Boxed Warning” for Evenity? Evenity may increase the risk of heart attack, stroke, or cardiovascular death. It should not be used in patients who have had a heart attack or stroke within the past year.

4. Does Milan Medicals ship Evenity to the UAE and USA? Yes. Evenity requires strict temperature control. We provide validated cold-chain shipping to the USA, UAE, KSA, UK, and Canada, ensuring the medication remains stable at 2°C to 8°C during international transit.

5. What happens after the 12-month Evenity course? The bone-building effect of Evenity begins to wane after 12 months. Most doctors will transition you to an anti-resorptive medication (like a bisphosphonate or Prolia) to maintain the new bone density you have gained.