Endokine 300 Injection

Product Details

Endokine 300 Injection contains Filgrastim, a granulocyte colony-stimulating factor (G-CSF) that stimulates white blood cell production. It is used to prevent infections in patients with low white blood cell counts due to chemotherapy, bone marrow transplants, or chronic neutropenia. Additionally, it is sometimes used as an adjunct in IVF (In Vitro Fertilization) to support endometrial growth and improve implantation rates in infertility treatments.

Uses:

1. Neutropenia Prevention: Reduces infection risk in chemotherapy and bone marrow transplant patients.
2. Stem Cell Mobilization: Facilitates the collection of peripheral blood progenitor cells for transplantation.
3. Bone Marrow Disorders: Treats severe chronic neutropenia.
4. IVF and Infertility Treatments: Supports endometrial lining growth and improves implantation rates in IVF cycles.

How It Works:

Filgrastim promotes the production and release of neutrophils, enhancing the immune system’s ability to fight infections. In IVF, it is believed to improve the endometrial environment, aiding embryo implantation.

Common Side Effects:

• Bone pain
• Fatigue
• Fever
• Nausea
• Injection site reactions

Serious Side Effects (Seek Immediate Medical Attention):

• Splenic rupture (pain in the left upper abdomen or shoulder)
• Severe allergic reactions (rash, swelling, difficulty breathing)
• Capillary leak syndrome (swelling, difficulty breathing, low blood pressure)

Key Features:

• Contains Filgrastim, a G-CSF that enhances immunity and cell growth.
• Prevents infections and supports recovery in neutropenic patients.
• Beneficial as an adjunct in IVF to support endometrial growth.
• Administered via injection under medical supervision.

Precautions:

• Pregnancy and Breastfeeding: Use during pregnancy only if prescribed by a doctor.
• Blood Counts Monitoring: Regular blood tests are required to monitor effects.
• Allergies: Inform your doctor about any known allergies to Filgrastim or similar products.

Frequently Asked Questions (FAQ):

1. What is Endokine 300 Injection used for?
It is used to increase white blood cell production in patients undergoing chemotherapy, bone marrow transplants, or with chronic neutropenia. It is also used as a supportive treatment in IVF cycles to improve embryo implantation.

2. How does Endokine 300 Injection help in IVF?
It is believed to improve the endometrial environment, making it more receptive for embryo implantation, thus enhancing the chances of a successful pregnancy.

3. How is Endokine 300 administered?
It is administered as a subcutaneous or intravenous injection under the supervision of a healthcare provider.

References:

1. Filgrastim and Its Applications – https://www.mayoclinic.org/drugs-supplements/filgrastim-injection-route/description/drg-20071547
2. Filgrastim in IVF – https://medlineplus.gov/druginfo/meds/a692033.html