Synacthen 250 mcg Injection contains tetracosactide, a synthetic analogue of adrenocorticotropic hormone (ACTH). It stimulates the adrenal cortex to produce corticosteroid hormones, including cortisol, allowing healthcare professionals to assess adrenal gland function.
The short-acting Synacthen injection is used as a diagnostic aid in the investigation of suspected adrenal insufficiency. It is commonly used in an ACTH stimulation test, in which cortisol levels are measured before and after administration.
Synacthen is a prescription medicine intended for use under appropriate medical supervision. The standard short-acting ampoule must not be confused with Synacthen Depot, which is a different formulation with different product instructions.
Synacthen 250 mcg Injection may be used by healthcare professionals for:
The results must be interpreted by a qualified healthcare professional alongside the patient’s medical history, laboratory findings and applicable diagnostic criteria.
Synacthen 250 mcg Injection should be administered only by qualified healthcare professionals according to the approved product instructions and the diagnostic protocol.
A commonly used adult short Synacthen test involves a single 250-microgram dose, with cortisol measurements taken before administration and at a specified interval afterwards. The route, sampling schedule and interpretation must follow the applicable clinical protocol.
Do not self-administer this medicine or use it for repeated treatment unless a specialist and the specific product authorization explicitly direct otherwise. The short-acting Synacthen ampoule is intended for diagnostic use in the referenced UK product information.
Possible adverse effects include:
Serious allergic reactions, including anaphylaxis, can occur. Administration should take place in a suitable clinical setting where the patient can be observed and emergency treatment is available.
Seek immediate medical attention for difficulty breathing, swelling of the face or throat, widespread hives, collapse or other signs of a severe allergic reaction.
Before administration, the healthcare professional should review the patient’s medical history, previous reactions to ACTH-related medicines and current treatments.
Important precautions include:
Refer to the official product leaflet for complete contraindications, warnings and precautions.
Store Synacthen according to the exact manufacturer’s instructions. The referenced product information specifies refrigeration at 2–8°C and protection from light.
Keep the ampoules in their original packaging where appropriate. Do not use the medicine after its expiry date or if the ampoule is damaged or the solution does not meet the product’s stated appearance requirements. Follow local requirements for pharmaceutical disposal.
For Synacthen 250 mcg injection pricing, ampoule sizes and availability, contact the supplier to confirm the exact product, manufacturer, current stock and cold-chain shipping arrangements.
Availability, prescription requirements and regulatory authorization differ by country. Confirm that the product is authorized for the intended use in the destination market and that refrigeration can be maintained throughout storage and transport.
1. What is Synacthen 250 mcg Injection used for?
It is used as a diagnostic aid to investigate suspected adrenal insufficiency by stimulating adrenal hormone production.
2. What is the active ingredient in Synacthen?
The active ingredient is tetracosactide, also called tetracosactrin, a synthetic ACTH analogue.
3. What is the strength of Synacthen 250 mcg Injection?
The standard short-acting presentation contains 250 micrograms of tetracosactide in a 1 mL ampoule, equivalent to 250 micrograms/mL.
4. Is Synacthen the same as Synacthen Depot?
No. Synacthen ampoules and Synacthen Depot are different formulations. Their duration of action, indications and instructions differ.
5. What is the price of Synacthen 250 mcg Injection?
Pricing depends on the supplier, pack size, market and cold-chain requirements. Contact the supplier for a current quotation.
6. Does Synacthen require refrigeration?
The referenced product information specifies storage at 2–8°C with protection from light. Always follow the storage directions on the exact product packaging.
7. Can Synacthen be administered at home?
It is intended for administration under appropriate healthcare supervision because diagnostic sampling must be coordinated and serious allergic reactions are possible.
This description is for general product information and does not replace professional medical advice, diagnosis or treatment. Synacthen should be administered only under appropriate medical supervision. Consult the official product leaflet for approved indications, diagnostic procedures, contraindications, storage conditions and complete safety information.
Last Updated: October 25, 2026
Orders ship from our India Head Office within 1–2 business days of confirmation. We include full customs documentation — HS codes, certificates of origin, and pharmaceutical export permits.
Estimated delivery: 3–7 business days to UK. 7–10 business days to UAE, Saudi Arabia and Gulf countries. 10–15 days for USA and Asian countries.
All packages arrive in plain, unmarked brown boxes. No pharmacy name or medication details on the outside.
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