Buy Trazodone 100 mg Tablets online in the UK. Each tablet contains 100 mg of trazodone hydrochloride, an antidepressant used for depression and anxiety. In the UK it is a prescription-only medicine (POM), so a valid prescription is needed for your order. See today’s price above and add it to your cart.
Trazodone changes how serotonin works in the brain. It treats the symptoms of depression and anxiety; it is not a quick fix and it should only be used as directed by a prescriber. Approved uses and legal status differ between countries, so this page shows them for the UK, Australia, the USA, the UAE and Russia.
Depression: the UK product information lists depression as a main use, including depression that comes with anxiety. In the USA the tablets are indicated for major depressive disorder in adults.
Anxiety: UK product information also lists anxiety as an approved use, usually at a lower daily dose than for depression.
Sleep: trazodone is sometimes prescribed for sleep problems, but insomnia is not a listed use in the UK product information or the US label. Drugs.com notes that the American Academy of Sleep Medicine suggests it only when other treatments have failed or depression is also present.
Trazodone is for adults only. It is not for children or adolescents under 18.
Trazodone blocks the return of serotonin into nerve cells and also blocks certain serotonin receptors, as described in the Russian Vidal register. Serotonin helps regulate mood. Trazodone is also sedating, which is why the NHS says a daily dose of 300 mg or less is usually taken once at bedtime.
The UK product information says depression in adults usually starts at 150 mg a day, taken in divided doses after food or as one dose at bedtime, and can rise to 300 mg a day. For anxiety it lists 75 mg a day, rising to 300 mg as needed. Very elderly or frail patients usually start at 100 mg a day. The NHS says to take trazodone with or after food and never to double up on a missed dose. Always follow the leaflet in the pack and the advice of your prescriber or pharmacist.
Dosing rules vary by country. The US label suggests starting at 150 mg a day in divided doses, raising by 50 mg a day every three to four days, with a maximum of 400 mg a day for outpatients. The US tablets are scored and can be taken whole or as a half tablet, shortly after a meal or light snack. Do not stop trazodone suddenly; your prescriber will reduce the dose gradually.
Serious reactions include a painful erection that will not go away (priapism), serotonin syndrome, an abnormal heart rhythm, yellowing of the skin or eyes, seizures and new or worsening suicidal thoughts. Seek urgent medical attention for any of these, and stop trazodone straight away if priapism occurs.
The US Medication Guide says to store trazodone tablets at 20°C to 25°C, in a tight container and away from light. Keep out of the reach of children and do not use after the expiry date on the pack.
Ordering Trazodone 100 mg Tablets takes a few minutes:
Questions before you order? Message a pharmacist on WhatsApp or call the support line shown on this page.
What is trazodone 100 mg used for?
It is an antidepressant used for depression and anxiety, according to UK product information. In the USA it is indicated for major depressive disorder in adults. Some prescribers use it for sleep problems, but that is not a listed use in the UK or US product information.
What is the active ingredient in trazodone 100 mg tablets?
Each tablet contains 100 mg of trazodone hydrochloride, an antidepressant that acts on serotonin in the brain. In the USA the same medicine is sold as generic trazodone HCl tablets, and the original brand name is Desyrel.
Is trazodone 100 mg available over the counter in the UK?
No. The NHS dm+d lists trazodone 100 mg tablets as a prescription-only medicine (POM) in the UK. It must be prescribed for you, and you can upload your prescription with your order for our pharmacist to check.
Do I need a prescription for trazodone in Australia or the USA?
Yes, in both countries. Trazodone is a Schedule 4 prescription-only medicine in Australia and a prescription medicine in the USA. You upload your prescription at checkout and our pharmacist checks it before dispatch.
Can trazodone 100 mg tablets cause drowsiness?
Yes. Drowsiness and dizziness are among the best-known effects, and UK leaflets say not to drive or use machines if you feel sleepy. They also advise avoiding alcohol, because trazodone can change how alcohol affects you.
Can children take trazodone 100 mg tablets?
No. UK leaflets say trazodone should not be used under 18 years, and the US label says it is not approved for pediatric patients. Antidepressants can raise the risk of suicidal thoughts in children, adolescents and young adults.
How long can I take trazodone 100 mg?
Your prescriber decides. The NHS says that after you have felt better for six months or more, your doctor may suggest stopping, usually by reducing the dose gradually. Do not stop suddenly or just because you feel better.
How do I buy trazodone 100 mg tablets online?
Choose your pack, add it to your cart and upload your prescription at checkout or on the Upload prescription page. Our pharmacist checks it before dispatch. Then check out securely and follow your order from your account.
Do you deliver trazodone to the UK, Australia, the USA, the UAE and Russia?
Yes. We deliver to the UK, Australia, the USA, the UAE, Russia and many other countries. Delivery options and the estimated delivery time for your country are shown at checkout before you pay. A valid prescription is still required.
How long does delivery take?
The estimated delivery time for your country is shown at checkout before you pay. Customs procedures in the destination country can affect timing, so check your order details carefully before you confirm.
What payment methods do you accept?
The available payment options are shown at checkout, each with simple instructions. Your order is processed once payment is confirmed and your prescription has been checked by our pharmacist.
Can I return or cancel my order?
Orders cannot be cancelled once placed, and refunds follow our Shipping, Returns and Refunds policy. Please check your order and prescription details carefully before you confirm.
This page provides general product information and does not replace professional medical advice, diagnosis or treatment. Trazodone is a prescription antidepressant and must be taken only as directed by your prescriber. Follow the official product information and the guidance of a healthcare professional.
Last Updated: October 27, 2026
Orders ship from our India Head Office within 1–2 business days of confirmation. We include full customs documentation — HS codes, certificates of origin, and pharmaceutical export permits.
Estimated delivery: 3–7 business days to UK. 7–10 business days to UAE, Saudi Arabia and Gulf countries. 10–15 days for USA and Asian countries.
All packages arrive in plain, unmarked brown boxes. No pharmacy name or medication details on the outside.
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