Spironolactone 100mg Tablet is a prescription potassium-sparing diuretic, aldosterone antagonist and antiandrogen used in the management of conditions including edema, heart failure, hypertension and hyperaldosteronism. Because spironolactone also has antiandrogenic activity, it is prescribed in selected patients for hormonal acne and may be used as an antiandrogen in feminizing hormone therapy (HRT) under appropriate medical supervision.
Aldactone® is a reference brand containing spironolactone. An appropriately authorized generic Spironolactone 100mg Tablet contains the same active pharmaceutical ingredient, although manufacturer, formulation, packaging and regulatory status can vary between markets.
Spironolactone is a mineralocorticoid receptor antagonist with potassium-sparing diuretic and antiandrogenic properties.
It blocks the action of aldosterone, a hormone that promotes sodium and water retention. By reducing aldosterone activity, spironolactone increases the elimination of sodium and water while reducing potassium loss.
Spironolactone also has antiandrogenic effects. This makes it clinically useful in selected patients with hormonal acne and as an antiandrogen in some feminizing HRT protocols.
Spironolactone 100mg may be prescribed for:
The approved uses of spironolactone differ between countries. Some dermatological and hormone-related uses may be off-label depending on the jurisdiction.
Spironolactone works through two clinically important mechanisms.
Spironolactone blocks mineralocorticoid receptors activated by aldosterone. This promotes sodium and water excretion while conserving potassium.
Spironolactone also reduces androgen-mediated effects. This can decrease androgen stimulation of sebaceous glands and other androgen-sensitive tissues.
This antiandrogenic activity explains its use in hormonal acne and as an androgen blocker in selected feminizing HRT regimens.
Spironolactone is commonly prescribed for hormonal acne, particularly when androgen activity contributes to persistent or recurrent acne.
Its antiandrogenic effects may reduce androgen-driven sebum production and help control acne breakouts in appropriate patients.
Spironolactone is not an antibiotic. It addresses hormonal pathways that may contribute to acne and is generally considered when conventional acne treatments are inadequate or hormonal factors are clinically relevant.
Hormonal acne frequently affects the chin, jawline and lower face and may fluctuate with hormonal changes.
Spironolactone can reduce androgen activity and may therefore help reduce excess oil production and acne in selected patients.
A 100mg tablet represents a higher tablet strength than 25mg or 50mg formulations. The appropriate dose for acne varies by patient and should be established by a healthcare professional.
Spironolactone 100mg may be prescribed as an antiandrogen in feminizing hormone therapy (HRT).
Its purpose in HRT is to reduce androgen activity. Spironolactone is not estrogen and does not replace estrogen therapy.
Depending on the treatment plan, it may be prescribed alongside estrogen under specialist supervision.
Medical monitoring may include:
HRT protocols differ between countries and individual patients, so treatment should be medically individualized.
Spironolactone has antiandrogenic properties that can reduce the effects of testosterone and other androgen hormones.
It may be used in selected patients for:
The appropriate dose depends on the treatment objective and individual patient factors.
Spironolactone may be prescribed to manage edema and fluid retention associated with selected cardiovascular, hepatic and renal conditions.
It promotes sodium and water excretion while conserving potassium.
The underlying cause of edema should be diagnosed before treatment, as appropriate therapy depends on the underlying condition.
Spironolactone is an established aldosterone antagonist used in appropriate patients with heart failure.
By blocking aldosterone, it can reduce sodium and fluid retention and provide additional cardiovascular benefits in selected patients.
Patients receiving spironolactone for heart failure require appropriate monitoring of kidney function and serum potassium.
Spironolactone can lower blood pressure and may be prescribed for hypertension, particularly when excess aldosterone contributes to elevated blood pressure or when additional antihypertensive treatment is required.
Spironolactone is commonly used for primary hyperaldosteronism because it blocks the effects of excessive aldosterone.
The required total daily dose depends on the severity of aldosterone excess, treatment response and individual patient factors.
Aldactone® is a reference brand containing spironolactone.
An appropriately authorized generic Spironolactone 100mg product contains the same active pharmaceutical ingredient. Manufacturer, inactive ingredients, packaging and regulatory authorization can differ by market.
Common commercial searches include:
Spironolactone 100mg, Generic Spironolactone 100mg, Aldactone 100mg, Generic Aldactone 100mg, Spironolactone 100mg Tablet, Spironolactone for Acne, Spironolactone HRT, Spironolactone Antiandrogen and Spironolactone 100mg for Feminizing HRT.
The appropriate spironolactone dose depends on the indication, clinical response, kidney function, serum potassium, blood pressure and other medicines.
A 100mg tablet may be used as part of an individualized treatment regimen for certain conditions. The dose required for acne, HRT, edema, hypertension or hyperaldosteronism can differ substantially.
Do not use the 100mg strength simply because it is a higher-strength tablet. Your healthcare professional should determine the appropriate dose and treatment schedule.
Do not increase, decrease or discontinue spironolactone without medical advice.
Possible side effects include:
Because of its antiandrogenic effects, gynecomastia may occur in some men.
Hyperkalemia, or excessively high potassium, can be serious and is more likely in patients with kidney impairment or those taking other potassium-raising medicines.
Healthcare professionals may monitor:
Monitoring is particularly important after treatment initiation or dose changes and in patients with kidney impairment or those taking other potassium-affecting medicines.
Spironolactone is a potassium-sparing medicine and can increase potassium levels.
The risk of hyperkalemia may be increased by:
Do not take potassium supplements or potassium-containing salt substitutes unless specifically recommended by a healthcare professional.
Potentially important interactions include:
Tell your healthcare professional about all prescription medicines, over-the-counter medicines, vitamins and supplements before starting treatment.
Spironolactone 100mg Tablet is a prescription medicine supplied through appropriately licensed pharmacies and pharmaceutical suppliers.
Commercial search intent includes Spironolactone 100mg Tablet, Buy Spironolactone 100mg, Buy Spironolactone Online, Generic Spironolactone 100mg, Generic Aldactone 100mg, Aldactone 100mg, Spironolactone 100mg Price, Spironolactone Supplier, Spironolactone Online Pharmacy, Spironolactone for Acne, Spironolactone HRT, Spironolactone Antiandrogen, Spironolactone for Feminizing HRT, Spironolactone 100mg for Hormonal Acne and Spironolactone 100mg HRT.
Availability, prescription requirements, approved indications and import regulations vary across the USA, UK, UAE/Dubai, Australia, Singapore, Thailand, China and Russia.
Spironolactone 100mg may be prescribed for edema, heart failure, hypertension and hyperaldosteronism. It may also be prescribed for hormonal acne and as an antiandrogen in selected feminizing HRT regimens.
The generic name is spironolactone.
Aldactone is a reference brand containing spironolactone. An appropriately authorized generic spironolactone product contains the same active pharmaceutical ingredient.
Yes. Spironolactone is commonly prescribed for hormonal acne because of its antiandrogenic activity. Acne treatment may be an off-label use depending on the country.
A healthcare professional may prescribe spironolactone at different doses for hormonal acne depending on the patient and clinical response. A 100mg tablet should not be taken without an appropriate prescription and medical assessment.
Yes. Spironolactone may be prescribed as an antiandrogen in feminizing HRT to reduce androgen activity. It does not replace estrogen therapy.
It may be used in some feminizing HRT regimens as an androgen blocker. Treatment should be individualized and monitored by a qualified healthcare professional.
Spironolactone is not an estrogen. In feminizing HRT, it is primarily used for its antiandrogenic effects.
Yes. Spironolactone is a potassium-sparing diuretic and aldosterone antagonist.
Yes. Spironolactone can increase serum potassium and may cause hyperkalemia.
Healthcare professionals commonly monitor serum potassium and kidney function, particularly after treatment initiation and dose changes.
Spironolactone is a prescription medicine. It should be obtained through an appropriately licensed pharmacy or authorized pharmaceutical supplier and used under medical supervision.
Spironolactone is marketed in many countries, although formulations, approved indications, prescription requirements and brand names vary between markets.
Medical Disclaimer: This product information is provided for educational and informational purposes only and is not a substitute for professional medical advice, diagnosis or treatment. Spironolactone is a prescription medicine that can increase serum potassium, affect kidney function and interact with numerous medicines. Its use for acne and feminizing HRT should be individually assessed by a qualified healthcare professional. The appropriate indication, dose, monitoring and treatment duration depend on the patient’s clinical circumstances. Always consult a healthcare professional before starting, stopping or changing spironolactone treatment.
Last Updated: August 23, 2026
Orders ship from our India Head Office within 1–2 business days of confirmation. We include full customs documentation — HS codes, certificates of origin, and pharmaceutical export permits.
Estimated delivery: 3–7 business days to UK. 7–10 business days to UAE, Saudi Arabia and Gulf countries. 10–15 days for USA and Asian countries.
All packages arrive in plain, unmarked brown boxes. No pharmacy name or medication details on the outside.
Spironolactone 100mg Tablet
Reviews
There are no reviews yet