Vilazodone 40 mg tablets contain vilazodone hydrochloride, an antidepressant medication known by the brand name Viibryd in the United States. The medicine is indicated for the treatment of major depressive disorder (MDD) in adults under US prescribing information.
Vilazodone acts on serotonin signalling in the brain. It is described pharmacologically as a serotonin reuptake inhibitor and 5-HT1A receptor partial agonist. Its precise clinical mechanism for treating depression is not fully understood.
The 40 mg tablet is one of the available strengths. In US prescribing information, the recommended target dosage is 20 mg to 40 mg once daily with food. Treatment is normally started at a lower dose and increased gradually under the prescriber’s direction. The 40 mg strength should not be treated as an automatic starting dose for a new patient.
| Product attribute | Details |
|---|---|
| Product name | Vilazodone 40 mg Tablets |
| Active ingredient | Vilazodone hydrochloride |
| Strength | 40 mg per tablet |
| Dosage form | Oral tablet |
| Therapeutic category | Antidepressant |
| Pharmacological description | Serotonin reuptake inhibitor and 5-HT1A receptor partial agonist |
| Reference brand | Viibryd |
| Main US-labelled indication | Major depressive disorder in adults |
| Route of administration | Oral |
| Food requirement | Take with food, according to prescribing information |
| Prescription status | Depends on local law; prescription-only in the United States |
| Manufacturer | Confirm from the specific product packaging |
| Pack size | Confirm from the specific product listing |
| Market authorization | Confirm for the country where the product will be supplied |
In the United States, vilazodone is indicated for the treatment of major depressive disorder in adults. Major depressive disorder can involve persistent low mood, loss of interest or pleasure, changes in sleep or appetite, reduced energy, difficulty concentrating, feelings of worthlessness, and other symptoms that affect everyday functioning.
A healthcare professional determines whether vilazodone is suitable after evaluating symptoms, medical history, current medicines, previous treatment, and relevant safety considerations. The indication and authorization may differ by country, so the local product information should be checked before describing the medicine as approved for a specific use in another market.
Vilazodone is not an immediate-relief medicine. Improvement may take several weeks, and follow-up is important to assess response and tolerability.
Vilazodone affects serotonin, a neurotransmitter involved in mood and other functions. It inhibits serotonin reuptake and acts as a partial agonist at the 5-HT1A receptor. These actions influence serotonin signalling, although the exact way they produce antidepressant effects is not fully established.
The prescribed dose and treatment duration depend on the patient’s response, tolerability, medical history, and the clinician’s assessment. Patients should not increase the dose or change the treatment schedule without medical advice.
The prescribed dose must be determined by a qualified healthcare professional. Under US prescribing information, the recommended target dosage for adults is 20 mg to 40 mg once daily with food.
The US label describes gradual dose adjustment beginning with 10 mg once daily with food for 7 days, followed by 20 mg once daily. The dose may be increased to 40 mg once daily with food after a minimum of 7 days between dose increases, as directed by the prescriber.
Important administration points:
The dosing schedule above reflects US prescribing information and is not a personalized treatment recommendation.
Vilazodone can cause side effects. Those reported in clinical studies include:
Other adverse effects may occur. The likelihood and severity can vary from person to person, and the complete patient leaflet should be consulted for the product supplied in the relevant market.
Seek urgent medical attention for serious symptoms, including signs of serotonin syndrome, a severe allergic reaction, seizures, unusual bleeding, or a sudden worsening of mental health. Any new or worsening suicidal thoughts require immediate attention from a healthcare professional or emergency service.
Suicidal thoughts and behaviours: Antidepressants carry a warning about an increased risk of suicidal thoughts and behaviours in children, adolescents, and young adults in short-term studies. Patients of all ages should be monitored for worsening depression, unusual behavioural changes, or emerging suicidal thoughts, particularly when treatment starts or the dose changes. US labelling does not approve Viibryd for paediatric use.
Serotonin syndrome: This potentially serious reaction can occur when medicines that affect serotonin are combined and may also occur with vilazodone alone. Symptoms can include agitation, confusion, sweating, fever, rapid heartbeat, tremor, muscle stiffness, or coordination problems. Seek urgent medical assessment if serotonin syndrome is suspected.
Bipolar disorder: Before starting an antidepressant, the prescriber should assess for a personal or family history of bipolar disorder, mania, or hypomania. Antidepressant treatment may trigger a manic or hypomanic episode in susceptible patients.
Bleeding risk: Vilazodone may increase bleeding risk, particularly when taken with aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), antiplatelet medicines, warfarin, or other anticoagulants.
Seizures: Patients with a seizure disorder or relevant risk factors require clinical assessment and monitoring.
Low sodium: Antidepressants can be associated with hyponatraemia, including cases related to SIADH. Older adults and people taking diuretics or otherwise at risk may need closer monitoring.
Discontinuation symptoms: Abruptly stopping treatment or reducing the dose too quickly can cause symptoms such as dizziness, nausea, headache, irritability, anxiety, sleep disturbance, or unusual sensory sensations. Dose reduction should be planned with the prescriber.
Tell the prescribing clinician and pharmacist about all prescription medicines, non-prescription products, vitamins, and herbal supplements being used.
Important interaction groups include:
Do not start, stop, or combine medicines based only on product-page information. A pharmacist or prescriber should check the specific combination.
Viibryd is a brand name for vilazodone hydrochloride in the United States. Generic vilazodone contains the same active ingredient, but a particular generic product’s authorization, formulation, manufacturer, and availability must be verified for its intended market.
| Comparison point | Vilazodone 40 mg generic | Viibryd 40 mg |
|---|---|---|
| Active ingredient | Vilazodone hydrochloride | Vilazodone hydrochloride |
| Strength | 40 mg per tablet | 40 mg per tablet |
| Brand status | Generic product, where authorized | Brand-name product |
| Main US-labelled indication | Major depressive disorder in adults | Major depressive disorder in adults |
| Administration | With food, according to product labelling | With food, according to product labelling |
| Manufacturer | Depends on the specific generic product | Depends on the brand supply and market |
| Availability | Varies by market and supplier | Varies by market and supplier |
Do not assume that all products labelled vilazodone are approved, interchangeable, or legally available in every country. Verify the exact product and applicable regulatory requirements.
Store the medicine according to the instructions on the specific product packaging and patient leaflet. Keep tablets in their original labelled container when appropriate, protect them from unsuitable storage conditions, and keep all medicines out of the reach of children. Do not use tablets beyond the expiry date.
1. What is Vilazodone 40 mg?
Vilazodone 40 mg is an oral tablet containing 40 mg of vilazodone hydrochloride, an antidepressant indicated for major depressive disorder in adults under US prescribing information.
2. Is Vilazodone 40 mg the generic version of Viibryd?
Yes. Viibryd is a US brand name for vilazodone hydrochloride. A specific generic product should still be checked for authorization and availability in the intended country.
3. What is Vilazodone 40 mg used for?
In the United States, vilazodone is indicated to treat major depressive disorder in adults. Use and authorization should be checked against local prescribing information in other countries.
4. Should Vilazodone 40 mg be taken with food?
Yes. US prescribing information instructs patients to take vilazodone with food because taking it without food can reduce absorption.
5. Is 40 mg the starting dose?
Not usually under the US-labelled titration schedule. Treatment starts at a lower dose and is increased gradually by the prescriber. Do not start or change to 40 mg without medical advice.
6. What are the common side effects?
Diarrhea, nausea, vomiting, and insomnia are among the side effects reported in clinical studies. Consult the specific patient leaflet for the full list.
7. Can Vilazodone cause serotonin syndrome?
Yes. It is a potentially serious risk, especially when vilazodone is combined with other medicines that affect serotonin. Seek urgent medical care if symptoms suggest serotonin syndrome.
8. Can Vilazodone be stopped suddenly?
Stopping suddenly can cause discontinuation symptoms. Speak with the prescriber about a gradual reduction plan rather than stopping independently.
9. Does Vilazodone interact with other medicines?
Yes. Important interactions include MAOIs, other serotonergic medicines, certain medicines affecting CYP3A4, and medicines that increase bleeding risk. A pharmacist or prescriber should review the complete medication list.
10. Is Vilazodone 40 mg available in every country?
No. Authorization, prescription requirements, brands, suppliers, and availability vary by country. Check the local medicines regulator and a licensed pharmacy.
11. Can Vilazodone 40 mg be purchased without a prescription?
Prescription requirements depend on local law. In the United States, vilazodone is a prescription medicine. Confirm the applicable rules in the country where the medicine will be supplied.
12. How long does Vilazodone take to work?
Antidepressant benefits may develop over several weeks. Follow-up with the prescriber helps assess improvement, side effects, and whether treatment needs adjustment.
This content is for general educational and product-information purposes only and is not a substitute for medical advice, diagnosis, or treatment. Vilazodone should be used only as prescribed by a qualified healthcare professional. Always follow the product’s official patient leaflet and the prescribing requirements in the relevant country.
Orders ship from our India Head Office within 1–2 business days of confirmation. We include full customs documentation — HS codes, certificates of origin, and pharmaceutical export permits.
Estimated delivery: 3–7 business days to UK. 7–10 business days to UAE, Saudi Arabia and Gulf countries. 10–15 days for USA and Asian countries.
All packages arrive in plain, unmarked brown boxes. No pharmacy name or medication details on the outside.
Only logged in customers who have purchased this product may leave a review.
Reviews
There are no reviews yet.